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Technology

Micro Invasive Technology, Inc., a Connecticut corporation, develops cutting edge imaging and therapeutic endoscopes for the next generation of minimally invasive surgical tools. Our endoscopic products
will offer higher quality images, reduced operating room workload, and increased
reliability over current instruments at a significantly lower cost.
Every year, nearly 2,000,000 patients incur hospital
infections; of these, nearly two thirds suffer infections that resist at least one antibiotic drug. Approximately 100,000 Americans die
annually from such hospital-bred infections. Our minimally invasive, near-term, pre-sterilized, disposable endoscopic products and future
therapeutic products are being designed to address these problems.
In response to increasing patient concern regarding an epidemic of such drug-resistant infections, medical device
manufacturers have expressed strong interest MITI’s disposable endoscope technology. Our
DirectView Products, are being designed to reduce both the risk of infection and the cost of
sterilization and, will soon be
available in rigid, semi-rigid and flexible models for office, clinic and hospital applications.
When combined with MITI’s digital imaging system, our
DirectView and TheraScope endoscopes will provide diagnostic, surgical and therapeutic capability for use in hospital, clinic
and office environments, thus creating a new, proprietary treatment modality.
DirectView ENDOSCOPIC
PRODUCTS
Rigid Endoscopes
Our DirectView endoscopes eliminate the eyepiece and endocoupler while providing a superior image connecting directly
to your camera. These endoscopes are far from "conventional," and
will include interchangeable viewing angles, eliminating the need for separate instruments for alternative views.
DirectView Products will include pre-sterilized, disposable rigid endoscopes targeted at new
FDA requirements that limit the use of re-processed
endoscopes. Priced under current market cost, DirectView endoscopes
will effectively offer a new, affordable instrument for each surgical procedure.
Flexible Endoscopes
Our DirectView flexible endoscopes
will incorporate “chip on a stick" technology with its proprietary, pre-sterilized disposable,
LightGuides. These flexible endoscopes are 5mm in diameter, 800mm in length,
and are designed for colonoscopy and gastro intestinal applications in the
office or clinic. Unlike fiber optic imaging systems, the MITI system utilizes
an articulated subminiature camera located at the endoscope's distal end
to obtain high quality images. The LightGuide
will provide a sterile barrier
that allows the camera to be used for multiple procedures without being re-sterilized.
Semi-rigid Endoscopes
We are now developing semi rigid DirectView endoscopes, combining a “chip on a stick” optical system with its proprietary, pre-sterilized disposable,
LightGuide. This 5mm diameter endoscope will employ articulation
control integrated into an ergonomic handle. The small diameter
will provide the ability to reach into smaller regions of the anatomy to acquire images from areas
that may be inaccessible to rigid endoscopes.
LightGuides
Our proprietary, pre-sterilized, disposable
LightGuides will provide illumination that transits the length of the device. Our
LightGuides will provide a sterile
barrier that allows the camera to be used for multiple procedures without
being re-sterilized. Interchangeable viewing angles
will be available for use with a single endoscope, and as either disposable or reusable units.
Diagnostic Medical
Office System
MITI has developed a medical office diagnostic system which includes a video monitor, light source, disposable endoscopes and computer-based digital camera system. The digital system also integrates patient history with diagnostic and surgical images, and stores them in the
computer's data base. Convenient flash memory, CD or tape capability provides archival storage.
TheraScope TECHNOLOGY

Our proprietary, therapeutic, technology,
TheraScope, combines digital imaging with therapeutic intervention in a single endoscopic device, thus harnessing the spectrum to “heal with light waves.” Our
Endoscopic PhotoActive Therapy has conclusively demonstrated in the laboratory this technology’s ability to destroy bacterial organisms such as staphylococcus with lightwaves in a matter of seconds. This new capability could provide the patient with better healthcare and greater safety, and surgeons with additional revenue.
MITI leads the way to “heal with light.” Our unique
TheraScope technology couples traditional imaging with new therapeutic capability,
Endoscopic PhotoActive Therapy. An endoscopic system is used to simultaneously view images from within the body and to perform therapeutic intervention procedures. This technology is targeted at antibiotic-resistant infection, foreign body reaction or a disease state such as cancerous tumors. Surgeons will be able to both image and intervene therapeutically using a single device.
Endoscopic
PhotoMicrobial Therapy
We are developing Endoscopic PhotoMicrobial Therapy
that combines lightwave therapy to which the pathogens have no defense
and endoscopic imaging. This physical technique may be used to supplement, or even replace traditional drug therapy. Specifically, a surgeon can sweep the bacteria-killing endoscope over
diseased tissue, including trocar ports, before closing, to eradicate or greatly diminish the potential for bacterial infection. Independent laboratory tests have shown that most bacteria and fungus are killed within seconds. The
TheraScope will enable surgeons to guide therapeutic light energy to kill infectious bacteria , thus, effectively,
to “heal with light.”
PhotoReactive Therapy
We are developing specialized rigid and flexible endoscopes using lightwaves to activate photo reactive anti-cancer agents and diagnostic dyes that show differential adhesion to tumors. These photo reactive dyes can be activated by the
TheraScope after injection into human tissue, generating images which cannot be viewed through a conventional endoscope.
Laser-Directing
Endoscopes
MITI’s laser-directing endoscopes will be designed to integrate therapeutic lasers with a target-marking capability analogous to weapons systems which shine beams of light on a target. The laser directing endoscopes are expected to be able to direct invisible laser energy through our endoscopes to
the area of ablation. The target image created by the endoscope is projected as an overlay on the monitor with a video image created by the endoscope.
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